BDBM279561 (3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3-hydroxy-5-((5-hydroxy-1,4,5,6-tetrahydropyrimidin-2-yl)amino)benzamido)acetamido)propanoic acid::US10035778, Example 2::US10577330, Example 2

SMILES OC1CNC(Nc2cc(O)cc(c2)C(=O)NCC(=O)N[C@@H](CC(O)=O)c2cc(Br)cc(c2)C(F)(F)F)=NC1

InChI Key InChIKey=CJRDXSVCUSRJDR-SFHVURJKSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 279561   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  2.70nMpH: 7.4 T: 2°CAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  2.70nMAssay Description:Recombinant human vitronectin (R& D Systems, 2308-VN) diluted to 1 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent